A SINGLE CENTERED PILOT STUDY TO EVALUATE THE EFFICACY OF AN ANTI ACNE FACE WASH (PURAC BF P/41 AND ACNACIDOL BG), IN SUBJECTS WITH ACNE VULGARIS
Acne is a chronic inflammatory skin condition of the pilosebaceous glands. The study aims to ascertain the effects of the face wash in acne management. The skin oiliness and porphyrin percentile was analyzed in relation to clinical improvement of the subjects. 30 subjects were treated to twice daily application of the face wash. Assessments were performed before the treatment commenced and after four weeks for the porphyrin percentile and the skin oiliness. The percentage of improvement in mean porphyrin percentile was 13.17% after four weeks.
The result of the skin oiliness determination clearly showed that there was a reduction in the sebum content after using the face wash for 4 weeks. This study demonstrated a sebosuppressive effect and antibacterial activity of the face wash. Therefore the study of the results clearly indicates that Anti Acne Face Wash has an additive effect in acne treatment and can be used as an adjuvant therapy for management of acne.
Abels C, Reich H, Knie U, Werdier D, and Lemmnitz G. (2014). “Significant improvement in mild acne following a twice daily application for 6 weeks of an acidic cleansing product (pH 4)”, Journal of Cosmetic Dermatology, Vol.13(2), pp.103-108.
Baumann LS, Penfield RD, Clarke JL, and Duque DK. (2014). “A Validated Questionnaire for Quantifying Skin Oiliness”, Journal of Cosmetics, Dermatological Sciences and Applications, Vol.4, pp.78-84.
Choi YS, Suh HS, Yoon MY, Min SU, Kim JS, Jung JY, Lee DH, and Suh DH. (2010). “A study of the efficacy of cleansers for acne vulgaris”, J. Dermatolog Treat., May, Vol.21(3), pp.201-205.
Del Rosso JQ. (2008). “Benzoyl Peroxide Cleansers for the Treatment of Acne Vulgaris: Status Report on Available Data”, CUTIS, Vol.82(5), pp.336-342.
Del Rosso JQ. (2009). “Moisturizers: function, formulation, and clinical applications”, In Draelos ZD. (ed). “Cosmeceuticals”, Saunders Elsevier, Philadelphia, PA, pp.97-102.
Del Rosso JQ. (2013). “The Role of Skin Care as an Integral Component in the Management of Acne Vulgaris: Part 1: The Importance of Cleanser and Moisturizer Ingredients, Design, and Product Selection”, J Clin Aesthet Dermatol, Dec, Vol.6(12), pp.19-27.
Del Rosso JQ, and Levin J. (2011). “The clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease-affected skin”, J Clin Aesthet Dermatol, Vol.4(9), pp.22-42. [PMC free article] [PubMed]
Dobrev H. (2010). “Fluorescence diagnostic imaging in patients with acne”, Photodermatology Photoimmunology and Photomedicine, Vol.26(6), pp.285-289. DOI: 10.1111/j.1600-0781.2010.00541.x
Draelos ZD, Ertel KD, and Berge CA. (2006). “Facilitating facial retinization through barrier improvement”, Cutis,Vol.78, pp.275-281. [PubMed]
Johny JM, Kulandhaivel M, Palaniswamy M, and Jose R. (2011). “Evaluation and In vitro Cell Line Studies of Phyto-Cosmeceutic Gel Based Hand Wash Formulation Using Camellia sinensis (Green Tea) And Myristica fragrans (Nutmeg)”, International Journal of Pharmaceutical & Biological Archives, Vol.2(4), pp.1218-1223.
Kuver S, and Palshikar G. (2014). “Formulation and evaluation of herbal Antiacne facewash”, International Journal of Phytotherapy Research, Issn 2278 – 5701, Vol.4(2), available online: http://earthjournals.org/ijpr_163.pdf.
Lebzelter J, and Elman M. (2002). “Evaluating Pulsed Light and Heat Energy in Acne Clearance”, Radiancy, available online: http://www.radiancy.com/images/stories/Support/Downloads/Published/5_AC.pdf.
Lee KR, Lee EG, Lee HJ, and Yoon MS. (2013). “Assessment of treatment efficacy and sebosuppressive effect of fractional radiofrequency microneedle on acne vulgaris”, Lasers Surg. Med., Vol.45, pp.639–647. doi: 10.1002/lsm.22200
Lee SH, Hub CH, Park KC, and Youn SW. (2006). “Effects of repetitive superficial chemical peels on facial sebum secretion in acne patients”, J Eur Acad Dermatol Venereol, Vol.20, pp.964-968.
Mukhopadhyay P. (2011). “Cleansers and their role in various dermatological disorders”, Indian J Dermatol, Jan-Feb, Vol.56(1), pp.2–6.
Sawarkar HA, Khadabadi SS, Mankar DM, Farooqui IA, and Jagtap NS. (2010). “Development and Biological Evaluation of Herbal Anti-Acne Gel”, International Journal of PharmTech Research, Vol.2(3), pp.2028-2031.
Solomon BA, and Shalita AR. (1996). “Effect of detergents in acne”, Clin Dermatol, Vol.14, pp.95-99.
Subramanyan K. (2004). “Role of mild cleansing in the management of patient skin”, Dermatol Titer, Vol.17, pp.26-34. [PubMed]
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