A COMPARATIVE STUDY BETWEEN CONVENTIONAL DRESSING OF ULCER AND DRESSING WITH TRIPLE HELICAL COLLAGEN
Abstract
When there is a wound anywhere in the skin, body heals itself because it is preprogrammed to respond with a series of complex sequential cellular and vascular activities. So to improve the life, treatment of the ulcer is necessary. The treatment of ulcer poses a significant challenge to clinicians. A total of 100 patients suffering from ulcer were taken randomly for this study after explaining the procedure and purpose of the study. This was a comparative study between conventional dressing of ulcer and dressing with triple helical collagen. There was significant difference in the result of collagen granules and conventional dressing. Collagen granules had better healing response rate and occasionally dramatic response. Considering the observations of this study we concluded that collagen granules are a useful topical agent to be applied locally to all types of ulcers except malignant ulcers.
Keywords
Full Text:
PDFReferences
Alvarez O, Hefton JM, and Eaglestein EW. (1984). “Healing wounds : occlusion or exposure”, Infection in Surgery, Vol.3, pp.173-181.
Aldrich. (1993). available at http://www.sigmaaldrich.com/catalog/product/sial/g2039?lang=en®ion=IN
Bates-Jensen B. (1995). “Wound C.A.R.E. An Acronym for Action”, JWOCN, Vol.22, pp.206-209.
Berglin EH, Edlund MB, Nyberg GK, and Carlsson J. (1982). “Potentiation by L-cysteine of the bactericidal effect of hydrogen peroxide in Escherichia coli”, Journal of Bacteriology, Vol.152(1), pp.81-88.
Bettmen AG. (1993). “Burns treatment of shock and toxaemia, healing of wounds. Reconstruction”, Am J. Surg, Vol.20, pp.33-37.
Bryant WM. (1977). "Wound Healing", Clinical Symposia, Vol.29, pp.2-36.
Clark RAF, Lanigan JM, DellaPelle P, Manseau E, Dvorak HF, and Colvin RB. (1982), “Fibronectin and fibrin provide a provisional matrix for epidermal cell migration during wound reep-ithelialization”, J. Invest. Dermatol., Vol.70, pp.264-269.
Coan CL. (1935). “Ferric chloride coagulation in treatment of burns with resume of tannic acid treatment”, Surg, Gyn & Obst. Vol.6, pp.687-692.
Davidson EC. (1925). “Tannic acid in the treatment of burns”. Surg. Gyn and Obst, Vol.41, pp.202-221.
Devis AH, and Bagstedt LR. (1964). “Principle of surgical physiology”, Paul and Hoebler, New York, p. 147-52.
Dingman RO, and Feclen I. (1960). “Semi-Open Method in the Management of the Burn Wound”, Plastic Reconst Surg., Vol.26(5), p.535-539.
Dunphy JE, Udupa KN, and Ewards IC. (1956). “Wound healing a new perspective with particular reference to ascorbic acid deficiency”, Ann. Surg., Vol.144, p.304.
Ebert RH, and Florey HW. (1939). “The extravascular development of the monocyte observedin vivo”, Brit. J. Exp. Pathol., Vol.20, p.342.
Edward LCS, and Dunphy JE. (1958). “Wound healing injury and normal repair”, N Engl J Med, Vol.25, p.224.
Ehrlich HP, and Hunt TK. (1968). “Effect of cortisone and vitamin A on wound healing”, Ann. Surg, Vol.167, p.324.
Gabbiani G, Chaponnier C, and Huttner I. (1978). “Cytoplasmic filaments and gap junctions in epithelial cells and myofibroblasts during wound healing”, J. Cell Biol., Vol.76, p.561-568.
Geronemus RG, and Robins P. (1982). “The Effect of Two New Dressings on Epidermal Wound Healing”, J Drem Surg Ocon, Vol.8, pp.850-852.
Gruber RP, Vistines L, and Pardol R. (1975). “Effect of commonly used antiseptics on wound healing”, J Plast Reconst. Surg., Vol.85, pp.472-476.
Hinman CD, and Maibach H. (1963). “Effect of Air Exposure and Occlusion on experimental Human Skin Wounds”, Nature, Vol.200, pp.377-378.
Jan R, and Hahuys M. (2001). “Indication of granulation tissue formation in chronic wounds by HA”, Wounds, Vol.13(4), pp.159-164.
Levenson SM, Birkhill FR, and Watermann DR. (1950). “The healing of soft tissue wounds, the effect of nutrition, anaemia and age”, Surgery, Vol.28, p.205.
Linksy CB, Rovee DT, and Dow T. (1981). “Effect of Dressings on Wound Inflammation and Scar Tissue”, in : Dineen P, and Hildick-Smith G. (eds). (1981). “The Surgical Wound”, Lea and febejer, Philadelphia, pp.191-205.
Meichior-Mac Dougall F, and Lander J. (1995). “Evaluation of Decision Tree for Management of Chronic Wounds”, JWOCN, Vol.22, pp.81-87.
Ninnikoski J, Hunt TK, and Dunphy JE. (1972). “Oxygen supply in healing tissue”, Am. J. Surg., Vol.123, p.247.
Peacock EE, and Winkle WV. (1976). “Wound Repair”, Saunders. Philadelphia, pp.1-21, 145-202, 215-231.
Potter PA, and Perry AG. (1993). “Fundamentals of nursing: concepts, process & practice”, 3rd edition, Mosby-Year Book, Inc, St. Louis, p.1666.
Rajbhandari SM, Harris ND, Tesfaye S, and Ward JD. (1999). “Early identification of diabetic foot ulcers that may require intervention using the microlight spectrophotometer”, Diabetes Care, Suh, Vol.22(8), pp.1292-1295.
Richard B, and Eisenman B. (1997). “Effect of skin dressing with topical antiseptic on wound healing of partial thickness of skin wound”, Textbook of Skin Healing, 6th edition.
Spector WG, and Lykke AWJ. (1966). “The cellular evolution of inflammatory granulomata”, J. Pathol. Bact., Vol.92, pp.163-167.
Sporn MB, and Roberts AB. (1986). “Peptide growth factors and inflammation, tissue repair, and cancer”, J. Clin. Invest., Vol.78, pp.329-332.
Taylor F. (1936). “The misuse of tannic acid”, J.A.M.A., Vol.106, pp.1144-1146.
Thomas S. (1990). “Wound cleansing agents”, in: “Wound Management Dressings”, The Pharmaceutical Press, Chapter 11, p.76.
Traccy AD, Ducate AE, Ward SI, and Yager DR. (2006). “Hyaluronan in human acute and chronic wounds”, Wound Repair and Regeneration, Vol.14(3), pp.252-258.
Trelease CA. (1986). “A Cost Effectiveness Approach for Promoting Skin Healing”, Nursing Economics, Vol.4(5), pp.__.
Vranckx JJ, Slama J, Preuss S, Perez N, Svensjö T, Visovatti S, Breuing K, Bartlett R, Pribaz J, Weiss D, and Eriksson E. (2002). “Wet Wound healing”, Plastic and reconstructive surgery, Vol.110(7), pp.1680-1687.
Vrijland WW, Tseng LNL, Eijkman HJM, Hop WCJ, Jakimowica JJ, Leguit P, Stassen LPS, Swank DJ, Haverlag R, Bonjer HJ, and Jeekel H. (2002). “Fewer Intraperitoneal Adhesions With Use of Hyaluronic Acid–Carboxymethylcellulose Membrane”, Annals of Surgery, Vol.235(2), pp.193-199.
Winter GD. (1962). “Formation of the scab and the rate of epithelialization of superficial wounds in the skin of the young domestic pig”, Nature, Vol.193, pp.293-294.
Wollina O, and Karamfilov T. (2000). “Treatment of recalutrant ulcers in pyodance gangrenosum with mycophenolate mofetil and aulotogous keratinocyte transplantation on a hyaluronic acid matrix”, Journal of the European Academy of Dermatology and Vencreology, Vol.14, p.187.
Refbacks
- There are currently no refbacks.
Send mail to ijsss@ijsss.com with questions or comments about this web site.
International Journal of Surgery and Surgical Sciences, All rights reserved.