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COMPARATIVE STUDY OF ROLE OF COLLAGEN PREPARATION AND CONVENTIONAL DRESSING IN DIFFERENT TYPES OF EXTERNAL ULCERS INCLUDING BURNS IN 100 CASES

Sabir Husain, Govind Yadav, Mohit Rawat, Umesh Jethwani, Vishal Dubey

Abstract


Introduction - Ulcer healing is a challenging task for every surgeon as well as a burden to the health infrastructure due long period of hospital stay, repeated dressing leading to economic burden to patients and the health provider. An ideal dressing material should help to control infection, reduces the pain and hasten the rate of healing without any complications. We evaluated role of collagen dressing in healing of ulcer.

Material & Methods - Hundered patients with ulcer were selected in this study and were allotted two groups based on computer generated random number collagen and conventional dressing. Dressings were changed according to standard protocol and wounds were examined for wound size, control of infection at the time of dressing.

Results - In 50 patients collagen dressings was applied, and conventional in rest 50 patients. The mean hospital stay in  conventional group  6.31+/-2.19 weeks & in collagen group 2.81+/- 1.02 weeks; P < 0.05  which  is  highly  significant  showing  collagen  dressings reduces hospital stay. Patient compliance was better for collagen dressings.

Conclusion - Collagen dressing is safe and effective in the treatment of ulcer and significantly reduces hospital stay, better cosmetic result, better patient compliance and reduced requirement of skin grafting.

Keywords


Ulcer, Collagen, Ulcer healing, Collagen preparation, Conventional dressing, External ulcers.

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References


Baker SR, and Stacey MC. (1994). “Epidiomology of chronic leg ulcers in Australia”, Australian and New Zealand Journal of Surgery, Vol.64, pp.258-261.

Callam MJ, Harper DR, Dale JJ, and Ruckley CV. (1987). “Chronic ulcers of leg: clinical history”, British Medical Journal, Vol.294, pp.1389-1391.

Cornwall JV Dore CJ, and Lewis JD. (1986). “Leg ulcer Epidiomology and etiology”, British Journal of Surgery, Vol.73, pp.693-697.

Donaghue VM, Chazan JS, and Rosenblum BI. (1998). “Evaluation of a collagen alginate wound dressing in the management of diabetic foot ulcers”, Adv Wound Care, Vol.11(3), pp.114-119.

Joshi IP, Bisht P, Sharma VK, and Uniyal D. (2003). "Studies on effect of nutrient media for clonal propagation of superior phenotypes of Dalbergia sissoo Roxb. Through tissue culture. Silvae Genet., Vol.52(3/4): pp.143-147.

Lee SK, Posthauer ME, Dorner B, Redovian V, Maloney MJ. (2006). “Pressure ulcer healing with a concentrated, fortified, collagen protein hydrolysate supplement: a randomized controlled trial”, Adv Skin Wound Care. Vol.19(2), pp.92-96.

Nayak P, Behera PR, and Thirunavoukkarasu M. (2007). "High frequency plantlets regeneration from cotyledonary node cultures of Aegle marmelos", (L.) in vitro Cell Dev. Biol. Plant, Vol.43, pp.231-236.

O‟ Barien JF, Grace PA, Perry IJ, and Burke PE. (2000). “Prevalence and Etiology of leg ulcers in Ireland”, Irish Journal of Medical Science, Vol.169(2), p.1.

Rao H, Pai A, Hussein I, Arun A, Ram HS, Pai A, Pai SR, and Pai SG. (2012). “A comparative study between collagen dressings and conventional dressings in wound healing”, International Journal of collaborative research on International Medicine & Public Health, Vol.4(5), pp.611-623.


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