

EXTRAPLEURAL PNEUMONECTOMY FOR MALIGNANT PLEURAL MESOTHELIOMA: A CASE REPORT
Abstract
Mesothelioma is an aggressive malignancy of the pleura with poor survival. It is an aggressive tumor arising from mesothelial cells lining the pleura. Multimodality treatment including neoadjuvant chemotherapy in selected individuals followed by extra pleural pneumonectomy and radiation has been studied in recent trials for its effects on disease free and overall survival.
We herein report a case of a 55 year old male, known case of Pulmonary Koch’s, initially evaluated elsewhere for breathlessness and fever of one month duration. CECT chest, CT guided FNAC and PET-CT allowed a conclusive diagnosis to be made. Patient underwent Right Extrapleural Pneumonectomy (including costal pleura, mediastinal pleura, part of pericardium and right dome of diaphragm) with Reconstruction of Diaphragmatic & Pericardial defect, and his postoperative course was uneventful. Extrapleural pneumonectomy has been encouraged since it allows thorough removal of gross tumor and can be associated with long-term survival. However, the EPP is still debated as optimal treatment of malignant pleural mesothelioma.
Keywords
References
Nowak AK. (2012). “Chemotherapy for malignant pleural mesothelioma: a review of current management and a look to the future”, Annals of Cardiothoracic Surgery, Vol.1(4), pp.508-515.
Rimner A, and Rosenzweig KE. (2012). “Novel radiation therapy approaches in malignant pleural mesothelioma”, Annals of Cardiothoracic Surgery, Vol.1(4), pp.457-461.
Takahashi K. (2004). “Emerging health effects of asbestos in Asia”, Proceedings of the Global Asbestos Congress, November, Tokyo, Japan.
Tan W, Harris E, Movsas B, Perry M, and Talavera F. (2011). “Mesothelioma”, available online: http://emedicine.medscape.com/article/280367-overview#showall.
Testa JR, et al. (1998). “Amulti-institutional study confirming expression of Simian virus 40 in MPM”, Cancer Res, Vol.58, pp.4505-4509.
Rice D. (2012). “Standardizing surgical treatment in malignant pleural mesothelioma”, Annals of Cardiothoracic Surgery, Vol.1(4), pp.497-501.
Robinson BWS, and Lake RA. (2005). “Advances in malignant mesothelioma”, The New England Journal of Medicine, Vol.353, pp.1591-1603.
Vogelzang NJ, Rusthoven JJ, and Symanowski J, et al. (2003). “Phase III study of pemetrexed in combination with cisplatin versus cisplatin alone in patients with malignant pleural mesothelioma”, Journal of Clinical Oncology, Vol.21(14), pp.2636-2644.
Weder W, and Opitz I. (2012). “Multimodality therapy for malignant pleural mesothelioma”, Annals of Cardiothoracic Surgery, Vol.1(4), pp.502-507.
Refbacks
- There are currently no refbacks.
Send mail to ijsss@ijsss.com with questions or comments about this web site.
International Journal of Surgery and Surgical Sciences, All rights reserved.