Open Access Open Access  Restricted Access Subscription Access

SURGICAL OPTIONS FOR STABLE LIP VITILIGO UNDER LOCAL ANESTHESIA

Krishna Talukdar, Kannauj Swargiri, Debdeep Mitra

Abstract


Introduction:  Lip Vitiligo is a challenging problem as it has a lot of cosmetic ramifications and has therapeutic limitations. Most of the medical management options for vitiligo are not optimum for depigmentation of lips. Surgical options for lip vitiligo have not been evaluated for their effectiveness. This study has tried to evaluate the efficacy of four of the standard surgical treatment options for lip vitiligo.

Material & Methods: A total of 16 patients with four patients in each group with stable lip vitiligo, i.e with atleast one year of no increase in the size of the lesion or any appearance of any new lesion, were treated with autologous melanocyte transfer, suction blister grafting, punch grafting and surgical excision and primary closure.

Results and Discussion: All patients were evaluated finally after six months of the procedure performed. All the patients operated by autologous melanocyte transplant noted excellent pigmentation and 75% of the patients operated by primary excision and closure noted excellent pigmentation. 75% of the patients operated by punch grafting technique had poor results and about 50% of the patients had poor results after suction blister grafting.

Conclusion: Autologous melanocyte transplantation is a novel and effective therarpeutic option for stable lip vitiligo. Although it requires state of the art dermato-surgery facilities and has a learning curve, but this study recommends it as the modality of choice in centers where facilities for mlanocyte transplant are available. Primary excision and suturing should be the modality of choice for centers with limited resources.

Keywords


Vitiligo, Surgery in vitiligo, Melanocyte, Suction Blister, Punch grafting, Lip vitiligo.

Full Text:

PDF

References


Falabella R. (1978). “Pigmentation of leucoderma by minigrafts of normal pigmented autologus skin”, J Dermatol. Surg. Oncol, Vol.4, pp.916-919.

Gupta S, Sandhu K, Kanwar A, and Kumar B. (2004). “Melanocyte transfer via epidermal grafts for vitiligo of labial mucosa”, J Dermatol Surg, Vol.30, pp.45-48.

Kachhawa D, and Kalla G. (2008). “Keratinocyte – Melanocyte graft technique followed by PUVA therapy for stable vitiligo”, Indian J Dermatol Venereol Leprol, Vol.74, pp.622-624.

Lerner AB, Halaban R, and Klaus SN, et al. (1987). “Transplantation of human melanocytes”, J Invest Dermatol, Vol.89, pp.219-224.

Mutalik S. (1993). “Transplantation of melanocytes by epidermal grafting: an Indian experience”, J Dermatol Surg Oncol, Vol.19, pp.231-234.

Njoo MD, Westerhof W, Bos JD, and Bossuyt PMM. (1998). “A systemic review of autologous transplantation methods in vitiligo”, Arch Dermatol, Vol.134, pp.1543-1549.

Pandya V, Parmar KS, Shah BJ, and Bilimoria FE. (2005). “A study of autologous melanocyte transfer in treatment of stable vitiligo”, Indian J Dermatol Venereol Leprol, Vol.71, pp.393-397.

Platt R, Brysk MM, and Newton RC, et al. (1989). “A surgical treatment for vitiligo : autologous cultured epithelil grafts”, J Dermatol Surg Oncol, Vol.15, pp.1161-1166.

Sacchidanand S, Purohit V, and Sujaya SN. (2011). “Surgical excision and primary closure for the treatment of lip vitiligo”, J Cutan Aesthet Surg, Vol.4, pp.216-217.


Refbacks

  • There are currently no refbacks.


Send mail to ijsss@ijsss.com with questions or comments about this web site. 

International Journal of Surgery and Surgical Sciences, All rights reserved.