A PROSPECTIVE STUDY OF FACTORS AFFECTING MORBIDITY AND MORTALITY IN PATIENTS OF NON TRAUMATIC PERFORATION PERITONITIS
Introduction: In every surgeon’s career perforation peritonitis is one of the common major surgical emergencies. In most of developing countries like India because of illiteracy, poverty, unavailability of proper health care facilities in rural areas and lack of knowledge and proper referral medical services in most of the cases presentation to hospital is late, with established generalised peritonitis associated with features of septic shock, signs and symptoms of multi-organ failure, so treatment without major morbidity and mortality in such patient is always a challenge even after various advancement in techniques of surgery, availability of broad spectrum antibiotics, improved intensive care facilities.
Method: A cross sectional prospective study was done including total 100 cases of Perforation peritonitis over a period of 2 years at tertiary care center in central Rajasthan India and observation of clinical presentation, Time duration of symptoms, intra-op findings done and outcome measured in terms of postoperative morbidity and mortality, statistical analysis of all data done with chi-square test.
Results: In our study total (62%) of total patients were found to be in the age group of 31 to 60 years and among them (79%) were male, (78%) of the patients presented after 48 hrs of appearance of symptoms. In our study we found that most common causes of perforation peritonitis were duodenal perforation (36 cases) followed by gastric (30), ileal (22 cases), Jejunum (4 cases), Appendicular (2 cases), Colon (5 cases), Rectum (1 cases), Gallbladder (1 case), Meckel's diverticulum (1 case). In this study Overall mortality was 14% and morbidity was approximately 49%.
Conclusion: In this study we concluded that direct relationship of morbidity and mortality was present to the time interval between occurrence and presentation to hospital with timely surgical intervention and amount of contamination in peritoneal cavity. Other predictors were co-morbid medical illness like anemia, deranged renal and liver function tests, nutritional status, post operative complications, post operative care and increasing age of the patient.
Adesunkanmi AK, Badmus TA, Fadiora FO, and Agbakwuru EA. (2005). “Generalized peritonitis secondary to typhoid ileal perforation: Assessment of severity using modified APACHE II score”, Indian J surg, Vol.67, pp.29-33.
Banerjee JC, and Bhattacharya PB. (1960). “A Handbook of Tropical Diseases with treatment and prescription”, 6th ed, Sec 3, Ch.1, pp.220-229, Academic publishers, Calcutta.
Dandapatt MC, Mukherjee LM, and Mishra SB. (1991). “Are view of 340 cases”, Ind J Surg, Vol.53(5), pp.189-193.
Desai LA, Mehta SJ, and Nadkarni KM. (1983). “A study of factors contributing to mortality”, Ind J Surg, Vol.45, pp.705-710.
Jhobta RS, Attri AK, Kaushik R, Sharma R, and Jhobta A. (2006). “Spectrum of perforation peritonitis in India-review of 504 consecutive cases”, World J Emerg Surg, Vol.1, p.26.
Khanna AK, and Mishra MK. (1984). “Typhoid perforation of the gut”, Postgraduate Medical Journal, Vol.60, p.523.
Memon AA, Siddiqui FG, and Abro AH, et al. (2012). “An audit of secondary peritonitis at a tertiary care university hospital of Sindh, Pakistan”, World J Emerg Surg, Mar, Vol.7, p.6.
Nadkarni KM, Shetty SD, Kagzi RS, Pinto AC, and Bhalerao RA. (1981). “A small bowel perforation A study of 32 cases”, Arch Surg, Vol.116, pp.53-57.
Patil PV, Kamat MM, and Hindalekar MM. (2012). “Spectrum of Perforative Peritonitis- A Prospective Study of 150 Cases”, Bombay Hospital Journal, Vol.54(1), pp.38-50.
Rajagopalan AE, and Pickleman J. (1982). “Free Perforation of the small Intestine”, AnnSurg, Vol.196, pp.576-576.
Sharma L, Gupta S, Soin AS, Sikora S, and Kapoor V. (1991). “Generalized peritonitis in India--the tropical spectrum”, Jpn J Surg, May, Vol.21(3), pp.272-277.
Singh G, Sharma RK, and Gupta A. (2006). “Gastrointestinal perforations- a prospective study of 342 cases”, Gastroenterology today, Oct Dec, Vol.10(4), pp.167-170.
- There are currently no refbacks.
Send mail to firstname.lastname@example.org with questions or comments about this web site.
International Journal of Surgery and Surgical Sciences, All rights reserved.