A COMPARATIVE STUDY TO ASSESS THE EFFECTIVENESS OF PROPHYLACTIC SYSTEMIC ANTIBIOTICS IN INGUINAL HERNIOPLASTY

Ramachandra J, K Athirath Reddy

Abstract


Introduction: Though there is no controversy in the use of prophylactic antibiotics in clean contaminated, contaminated and dirty wounds, there is still some controversy surrounding use of prophylactic antibiotics in clean wounds like Lichtenstein mesh hernioplasty. Inadvertent use of antibiotics in these cases leads to unnecessary increase in cost to the patient as well as development of antibiotic resistance, as development of resistance to antibiotics by microorganisms has become a growing concern in countries like India. Hence, we conducted a case control study at KIMS hospital, Bangalore from Dec 2014 to Nov 2016 to assess if systemic antibiotic prophylaxis prevents wound infection in Lichtenstein inguinal hernioplasty.

Materials & Methods: The study period was two years including follow-up, comprising of 100 cases randomized into two groups. First group (case group) received no antibiotics and the second group received 3rd generation cephalosporin (control group) prior to the surgery.

Results: The study revealed 2 cases of infection in the case group and 1 in the control group. The difference was statistically insignificant (p= 0.3436).

Conclusion: From our study it can be concluded that regular use of antibiotic prophylaxis is not necessary in low risk patients undergoing hernioplasty

Keywords


Antibiotics, Inguinal hernia, Lichtenstein repair, Hernioplasty, Wound infection, Mesh repair.

References


Aufenacker TJ, van Geldere D, van Mesdag T, Bossers AN, Dekker B, Scheijde E, van Nieuwenhuizen R, Hiemstra E, Maduro JH, Juttmann JW, Hofstede D, van Der Linden CTM, Gouma DJ, and Simons MP. (2004). “The Role of Antibiotic Prophylaxis in Prevention of Wound Infection after Lichtenstein Open Mesh Repair of Primary Inguinal Hernia. A Multicenter Double-Blind Randomized Controlled Trial”, Annals of Surgery, Vol.240(6), December, pp.932-938.

Goyal A, Garg R, Jenaw RK, and Jindal DK. (2011). “Role of Prophylactic Antibiotics in Open Inguinal Hernia Repair: A Randomised Study”, Indian J Surg, Vol.73(3), pp.190-193.

Li JF, Lai DD, Zhang XD, Zhang AM, Sun KX, Luo HG, and Yu Z. (2012). “Metaanalysis of the effectiveness of prophylactic antibiotics in the prevention of postoperative complications after tension-free hernioplasty”, Can J Surg, Vol.55(1), February, pp.27-32.

Najam-ul-Haq R, Chaudhry IA, Khan BA, and Afzal M. (2006). Groin Sepsis Following Lichtenstein Inguinal Hernioplasty without Antibiotics Prophylaxis: A Review of 100 Cases”, Pakistan journal of medical sciences, Vol.22(4), pp.416-419.

Sanabria A, Dominguez LC, Valdivieso E, and Gomez G. (2007). “Prophylactic Antibiotics for Mesh Inguinal Hernioplasty, A Meta-analysis”, Annals of Surgery, Vol.245(3), March.

Thakur L, Upadhyay S, and Peters NJ. (2010). “Prophylactic antibiotic usage in patients undergoing inguinal mesh hernioplasty — A clinical study”, Indian J Surg, Vol.72(3), pp.240-242.

Yerdel MA, Akin EB, and Dolalan S, et al. (2001). “Effect of single-dose prophylactic ampicillin and sulbactum on wound infection after tension-free inguinal hernia repair with polypropylene mesh: the randomized, double-blind, prospective trial”, Ann Surg, Vol.233, pp.26-33.


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